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Evaluate the effect of Yapana basti on biological markers of reproduction: A Case Series on Oligozoospermia

##article.authors##

  • Ankur Kumar Tanwar Ankur Tanwar All India Institute of Ayurveda, Sarita Vihar, New Delhi
  • Sujata Rajan Ayurvedic and Unani Tibbia college and Hospital, Govt. of NCT of Delhi
  • Manoj Shamkuwara Ayurvedic and Unani Tibbia College and Hospital, Govt of NCT of Delhi

DOI:

https://doi.org/10.53721/aca.8

Keywords:

Biomarkers, Infertility, Shukra, Oligozoospermia, Yapana Basti

Abstract

Background: Definition of Infertility is a couple inability to conceive baby after one year of regular unprotect sexual intercourse. In present era of urbanization and industrialization, there has been a drastic change in our lifestyle, dietary  habits, and sexual health. According to World health organisation(WHO), the overall incidence of  infertility as 16.7% globally and The male partner  is  responsible for around 30 to 40 % directly. The main cause of male infertility is Oligozoospermia(Shukra kshaya). Purpose: To determine the Effect of Yapana basti on biological markers(Serum FSH, Serum LH, Serum Testosterone) of Reproduction in  Population of Delhi -NCR. Design: Case series.Methods: Mustadi Yapana Basti was given to each participant for 15 consecutive days. The Oligozoospermia (Shukra Kshaya) Assessment through Questionnaire and Objective assessment (sperm count and serum biomarkers) was used to evaluate the prognosis as well as to find the therapetic effect. Data were collected two times before and one month after therapy. Results: Five study participants with a sperm count of less than 15 million/ml with a mean age of 29 years (range 25--40) were enrolled in the study. All five participants showed marked improvement at the end of treatment. Results were assessed by serum biomarkers of male reproductive health and semen analysis. Basti treatment gives a significant improvement in all the symptoms of Shukra Kshaya and semen parameters as well as on biomarkers in this case series. Conclusion: Yapana Basti shows a beneficial effect on serum biomarkers of spermatogenesis, and improved sperm count.

Author Biographies

Ankur Kumar Tanwar Ankur Tanwar, All India Institute of Ayurveda, Sarita Vihar, New Delhi

Ph.D. Scholar, Dept. of Kriya Sharir

Sujata Rajan, Ayurvedic and Unani Tibbia college and Hospital, Govt. of NCT of Delhi

Assosiate Professor and Head, Dept. of Kriya Sharir

Manoj Shamkuwara, Ayurvedic and Unani Tibbia College and Hospital, Govt of NCT of Delhi

Associate Professor and Head, Dept. of Panchakarma

References

Organization WHO. WHO laboratory manual for the Examination and processing of human semen. 5th ed. WHO Press; 2010.

Zegers-Hochschild F, Adamson GD, de Mouzon J, et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril. Nov 2009;92(5):1520-4. doi:10.1016/j.fertnstert.2009.09.009

Jurewicz J, Radwan M, Sobala W, Radwan P, Bochenek M, Hanke W. Effects of occupational exposure - is there a link between exposure based on an occupational questionnaire and semen quality? Syst Biol Reprod Med. Aug 2014;60(4):227-33. doi:10.3109/19396368.2014.907837

Knez J. Endocrine-disrupting chemicals and male reproductive health. Reprod Biomed Online. May 2013;26(5):440-8. doi:10.1016/j.rbmo.2013.02.005

Bonde JP. Occupational causes of male infertility. Curr Opin Endocrinol Diabetes Obes. Jun 2013;20(3):234-9. doi:10.1097/MED.0b013e32835f3d4b

Sharma R, Biedenharn KR, Fedor JM, Agarwal A. Lifestyle factors and reproductive health: taking control of your fertility. Reprod Biol Endocrinol. Jul 16 2013;11:66. doi:10.1186/1477-7827-11-66

Skoracka K, Eder P, Lykowska-Szuber L, Dobrowolska A, Krela-Kazmierczak I. Diet and Nutritional Factors in Male (In)fertility-Underestimated Factors. J Clin Med. May 9 2020;9(5)doi:10.3390/jcm9051400

Agarwal A, Mulgund A, Hamada A, Chyatte MR. A unique view on male infertility around the globe. Reprod Biol Endocrinol. Apr 26 2015;13:37. doi:10.1186/s12958-015-0032-1

Kumar N, Singh AK. Trends of male factor infertility, an important cause of infertility: A review of literature. J Hum Reprod Sci. Oct-Dec 2015;8(4):191-6. doi:10.4103/0974-1208.170370

Sharma R, Malviya R, Das Sj, Das S, Murthy RA. Management of Male Infertility: Ayurvedic Approach. International Research Journal of Pharmacy. 2013;4(6):6-7. doi:10.7897/2230-8407.04602

Durairajanayagam D. Lifestyle causes of male infertility. Arab J Urol. Mar 2018;16(1):10-20. doi:10.1016/j.aju.2017.12.004

Babakhanzadeh E, Nazari M, Ghasemifar S, Khodadadian A. Some of the Factors Involved in Male Infertility: A Prospective Review. Int J Gen Med. 2020;13:29-41. doi:10.2147/IJGM.S241099

Cooper TG, Noonan E, von Eckardstein S, et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update. May-Jun 2010;16(3):231-45. doi:10.1093/humupd/dmp048

McLachlan RI. Approach to the patient with oligozoospermia. J Clin Endocrinol Metab. Mar 2013;98(3):873-80. doi:10.1210/jc.2012-3650

Sushruta samhita, Chikitsa sthana, Netrabastipramanpravibhagchikitsikam, 35/3-5. Available from: https://niimh.nic.in/ebooks/esushruta/index.php.( Last accessed on 2021 June 5th )

Charaka samhita, Siddhi sthana, Kalpanasiddhiadhyaya, 01/40. Available from: https://niimh.nic.in/ebooks/ecaraka/index.php.( Last accessed on 2021 June 5th )

Sushruta samhita, Chikitsa sthana, Niruhakarmachikitsikam, 38/106-111. Available from: https://niimh.nic.in/ebooks/esushruta/index.php.( Last accessed on 2021 June 5th )

Charaka samhita, Siddhi sthana, Uttarabastisiddhiadhyaya, 12/16(1). Available from: https://niimh.nic.in/ebooks/ecaraka/index.php.( Last accessed on 2021 June 5th )

Sushruta samhita, Chikitsa sthana, Niruhakarmachikitsikam, 38/111. Available from: https://niimh.nic.in/ebooks/esushruta/index.php.( Last accessed on 2021 June 5th )

Sushruta samhita, Chikitsa sthana, Niruhakarmachikitsikam, 38/05. Available from: https://niimh.nic.in/ebooks/esushruta/index.php.( Last accessed on 2021 June 5th )

Charaka samhita, Chikitsa sthana, Vajikaranaadhyaya, 02(1)/16. Available from: https://niimh.nic.in/ebooks/ecaraka/index.php.( Last accessed on 2021 June 5th )

Charaka samhita, Siddhi sthana, Uttarabastisiddhiadhyaya, 12/21-22. Available from: https://niimh.nic.in/ebooks/ecaraka/index.php.( Last accessed on 2021 June 5th )

Anbu J, Nithya S, Kannadhasan R, Kishore G, Anjana A, Suganya S. Antioxidant and protective effect of aqueous extract of Ichnocarpus frutescens and Cyperus rotundus against cisplatin induced testicular toxicity in rodents.

Wani JA, Achur RN, Nema R. Phytochemical screening and aphrodisiac property of Tinospora cordifolia. studies. 2011;8:9.

Chauhan NS, Sharma V, Dixit VK, Thakur M. A review on plants used for improvement of sexual performance and virility. Biomed Res Int. 2014;2014:868062. doi:10.1155/2014/868062

Banjare L, Prasad AK, Naik M. Boerhaavia diffusa from traditional use to scientific assessment-a review. Int J Pharmaceut Biol Arch. 2012;3:1346-1354.

Santhosha D, Ramesh A, Prasad S, Kumar S, Kumar P, Dhanalakshmi C. Punarnava-a review. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2011;2(4):427-436.

Pareek A, Kumar A. Ethnobotanical and pharmaceutical uses of Vetiveria zizanioides (Linn) Nash: a medicinal plant of Rajasthan. Int J Life Sci Pharm Sci. 2013;50:L12-L18.

Chhatre S, Nesari T, Somani G, Kanchan D, Sathaye S. Phytopharmacological overview of Tribulus terrestris. Pharmacognosy reviews. 2014;8(15):45.

Adelakun SA, Ogunlade B, Olawuyi TS, Aniah JA, Omotoso OD. Histomorphology, Sperm Quality and Hormonal Profile in Adult Male Sprague-Dawley Rats following administration of aqueous crude Extract of Solanum nigrum by gastric gavage. JBRA assisted reproduction. 2018;22(4):338.

Evaluate the effect of Yapana basti on biological markers of reproduction-A Case Series on Oligozoospermia.

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Posted

2022-05-26