Preprint / Version 4

Ayurvedic Management of Diabetic Macular Odema- DME (Sannipataja Timira) - A Case Report


  • Shanti K Assistant Professor, Dept of Shalakya Tantra, Amrita School of Ayurveda
  • Remya RS Department of Shalakya Tantra, Amrita School of Ayurveda, Kollam, Kerala



Proliferative Diabetic Retinopathy, Anti VEG-F, Vidalaka, Anjana Karma, Case Report, Ayurveda


Background- Diabetic Macular edema (DME) is the primary cause of visual loss in Diabetic Retinopathy (DR). The hyperglycemic state promotes the activation of multiple interlinked pathways leading to DME. The current guidelines in contemporary science recommend anti-VEG-F injections as the first line of treatment for this condition. Repeated anti-VEG-F injections cause a lot of financial burden on the patient & their family, at the cost of very little visual outcome.

Symptoms like Aavila darshana (smoky vision) and signs like aneurysms, macular edema, and exudates suggested Tridosa vikriti (vitiation of all the 3 Dosas) according to Ayurveda and so, it was diagnosed as Sannipataja Timira.

Case & Intervention- A 53-year-old male patient sought Ayurvedic treatment when his vision in the right eye did not improve after the injection of Accentrix for Diabetic macular edema. His Ophthalmologist advised him to repeat the injection after 6 months but did not assure him of complete resolution of edema. So, he opted for Ayurvedic treatment. His treatment comprised internal medicines consisting of Punarnavadi kashaya, Guduchyadi kashaya, Chandraprabha vati, Gomutra haritaki lehya; external treatments like Talpodichil with punarnavadi churna and Pratimarsha nasya with Anu taila; Kriyakalpas (eye treatments) like Vidalaka and anjana Karma.

Outcome- At the end of 8 months of Ayurvedic treatment, his visual acuity improved from 6/60 to 6/6. Optical Coherence Tomography (OCT) affirmed complete normalcy of the macula.

Conclusion- Ayurvedic treatment is effective in reversing the process of macular edema, thereby bringing about marked visual outcomes in DME. Such patients should not be denied Ayurvedic treatment and subjected to expensive and invasive treatment procedures like intravitreal injections, even when the absolute effect of these remains doubtful.


Amoaku WM, Ghanchi F, Bailey C, Banerjee S, Banerjee S, Downey L, et al. Diabetic retinopathy and diabetic macular oedema pathways and management: UK Consensus Working Group. Eye (Basingstoke). 2020.

Falavarjani KG, Nguyen QD. Adverse events and complications associated with intravitreal injection of anti-VEGF agents: A review of literature. Eye (Basingstoke). 2013.

Paradakara HS, Editor. Astanga Hridaya of Vagbhatta, Uttarasthana. 9th ed.Ch. 12, Ver. 10. Varanasi: Chaukhambha Orientalia Publication; 2010. p. 817, 517

Ayurvedic Pharmacopoeia of India, Part 1,2nd ed:The controller of publications civil lines Delhi; 2003.p 187, 173, 512, 91,111,133.

Shivprasad Sharma, Editor. Astanga Samgraha of Vagbhatta, Utharasthana.9th ed. Ch.29,Ver.8. Varanasi: Choukhambha Orientalia Publication; 2010. p.223.

Krishnan Vaidyan A.K.V, Editor. Sahasrayogam, 2nd ch, Ver.2. 23rd ed. Vidyarambham publishers; 2000. p.390.

Paradakara HS, Editor. AstangaHridaya of Vagbhatta, Nidanasthana. 9th ed.Ch. 13, Ver. 31. Varanasi: ChaukhambhaOrientalia Publication; 2010. p. 502, 520.

Ayurvedic management of DME


2021-05-16 — Updated on 2021-08-31